This could be a breakthrough for colon cancer prevention.
Researchers at the Australian National University have learned how to use a drug to activate a cancer-blocking protein that can clear damaged DNA from the body “like a light switch.”
“In an activated state, the protein acts like a surveillance system, detecting signs of damaged DNA in our cells,” says researcher Dr. Abhimanu Pandey about the Ku70 protein.
He added that “damaged DNA” is usually an early warning sign that a cell could become cancerous. Ku70 has the potential to reverse or at least stop the damage.
“Our research shows that Ku70 can ‘cool down’ cancer cells and wipe out damaged DNA. The protein prevents cancer cells from becoming more aggressive and spreading throughout the body, essentially deactivating them and keeping them dormant.
Researchers say existing drugs can activate proteins that detect cancer warning signs. ChrisChrisW
In the United States, 126,240 cases of colorectal cancer were reported to the Centers for Disease Control and Prevention in 2020.
It claimed 51,869 lives that year.
In Australia where the research was conducted, 100 people die each week from some form of bowel cancer, according to the study.
However, 90% of cases can be treated successfully if detected early, according to the data, now published in Science Advances.
“We know early detection and treatment is important to overcome not only colon cancer but also potential other cancers,” said researcher Si Ming Man Man.
Researchers are excited about the potential this protein shows. jubaphoto
Man added that screening for cancers such as colon may soon include screening for Ku70 levels.
“Our research shows Ku70 is a good immune biomarker, meaning it helps us predict who will get better or worse after being diagnosed with bowel cancer.”
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Source: thtrangdai.edu.vn/en/
